No. From what you write the hard drive would not even be in the equation yet.
More likely the RAM or CPU.
You cold try removing all the RAM but one stick in slot one and interchanging the sticks if the first doesn't work etc.
Also clear your CMOS. Unplug the computer and remove the motherboard battery. Also if you see a 3 pin jumper labeled JBAT move the jumper sleeve from 1/2 to 2/3 and wait a few minutes. Then reset to 1/2 and replace the battery and power on.
ESD - What can I do to avoid damage