When I click on an icon it can take 5 or 10 minutes or even longer for the program to start. However, if I put the program into the Start file it will start immediately after boot up.

Can you help me please?

If this just started happening try a system restore.
Start/Run/ %systemroot%\system32\restore\rstrui.exe

Otherwise I would suggest defragging & run chkdsk:

start > run > cmd
in the new window type chkdsk/f
when prompted to run on boot choose Y & reboot
this will check for & fix any disk errors.

If the problem persists:
Also: look in your Event viewer: rt. click My Computer then click Manage then Event Viewer.
Or: Administrative Tools/Event Viewer or Start/Run/ eventvwr
Open the system as well as the application tabs & look for X errors. Click error line for details.
Post back the source & event id especially of errors that seem to coincide with this issue.

Do you have any other problems? Are you on a network? Do you run malware scans?

You might also try deleting the shortcut & then re-creating it from the program.

You might also want to try this route:

Please follow the instructions HERE & then post your log in a new thread in the Spyware, Adware, Viruses and HijackThis Logs section.
(Not in this section please).