anyone familar with this error. Just curious as to what it means and if it's detremental?

Event filter with query "SELECT * FROM __InstanceModificationEvent WITHIN 60 WHERE TargetInstance ISA "Win32_Processor" AND TargetInstance.LoadPercentage > 99" could not be reactivated in namespace "//./root/CIMV2" because of error 0x80041003. Events cannot be delivered through this filter until the problem is corrected.

See this.

That said, without knowing the timestamp or how old that error is, it is impossible to tell if it might be detrimental or not.

I have had this same issue each time I boot since August 2011. Finally had a good look at this today. The following link provides a FIX IT option so that the annoying notification can now cease:

Event ID 10 is logged in the Application log after you install Service Pack 1 for Windows 7 or Windows Server 2008 R2

This originated in the Windows 7 SP1 DVD/ISO creation process. There was an issue in the creation process that caused a WMI registration to remain in the DVD/ISO. Since the registration is designed to work only during the DVD/ISO creation process, it fails to run on a live system and causes these events. These events are not indicative of any issue in the system and can be safely ignored. If however you want to prevent these events from getting generated and want to remove this specific WMI registration manually, please follow the steps mentioned in this article for running the workaround script.