Hello everyone
I have Windows Vista Home Edition.
Any new application I try and run I encounter a block which is usually E:\setupstb.exe which says directory name is invalid.
However I am always getting shellexecuteEx failed; code 267. I have no clue on what to do at all. Please help!

Any new application I try and run I encounter a block

I need much more info.
What do you mean by "new" application?
Can you run any program?
Are you posting from the computer in question?

I can not download any new application what so ever. I can use everything I have now on my computer.
When I tried to install my new web cam I come up with the E:\setupstb.exe invalid directory name.
This also happens to any other application. I can click run but then I get a block.
I have been seeing C:/users/mom.appdata/local/microsoft/windows/temporaryinternetfiles/content.IE5/U5FF27RY/Driver-update[1].exe when I tried to download a new driver system.
Basically I can not run any program or install them... I'm not sure what to give you so if you need more information let me know.

Let's see, if we can look at your computer booting from an external source.

Please download OTLPE (filesize 120,9 MB)

• When downloaded double click on OTLPENet.exe and make sure there is a blank CD in your CD drive. This will automatically create a bootable CD.
• Reboot your system using the boot CD you just created.
  
  • Note : If you do not know how to set your computer to boot from CD follow the steps HERE
• Your system should now display a REATOGO-X-PE desktop.
• Depending on your type of internet connection, you should be able to get online as well so you can access this topic more easily.
• Double-click on the OTLPE icon.
• When asked Do you wish to load the remote registry, select Yes
• When asked Do you wish to load remote user profile(s) for scanning, select Yes
• Ensure the box Automatically Load All Remaining Users" is checked and press OK
• OTL should now start.
• Press Run Scan to start the scan.
• When finished, the file will be saved in drive C:\OTL.txt
• Copy this file to your USB drive if you do not have internet connection on this system
• Please post the contents of the OTL.txt file in your reply.

I really hate to say this but, when i tried to go and download OTLPENet.exe it would not let me....
I clicked run and it went through that stage and when it came to verifying OTLPENet it stopped and came up with this;
C:\Users/MOM\Appdata\local\Microsoft/Windows/TemporaryInternetFiles\Content.IE5\U5FF27RY\OTLPEN et[1].exe
The Directory name is invalid.
Now what should I do?

In that case, you'll need to use another working computer to create this CD.

Do you think I can do this if i access safe mode?

I doubt, but you can give it a shot.

I tried but that did not work. I have no means of any other computer source. Are there any other possible soultions you can think of that I could try?

I'm not sure, if we can do anything else since you can't run anything, but let's try something....

Please download ComboFix from Here or Here to your Desktop.

**Note: In the event you already have Combofix, this is a new version that I need you to download. It is important that it is saved directly to your desktop**

1. Please, never rename Combofix unless instructed.
2. Close any open browsers.
3. Close/disable all anti virus and anti malware programs so they do not interfere with the running of ComboFix.
   
   • Very Important! Temporarily disable your anti-virus, script blocking and any anti-malware real-time protection before performing a scan. They can interfere with ComboFix or remove some of its embedded files which may cause "unpredictable results".
   • Click on this link to see a list of programs that should be disabled. The list is not all inclusive. If yours is not listed and you don't know how to disable it, please ask.
   
   NOTE1. If Combofix asks you to install Recovery Console, please allow it.
   NOTE 2. If Combofix asks you to update the program, always do so.
   
   • Close any open browsers.
   • WARNING: Combofix will disconnect your machine from the Internet as soon as it starts
   • Please do not attempt to re-connect your machine back to the Internet until Combofix has completely finished.
   • If there is no internet connection after running Combofix, then restart your computer to restore back your connection.
4. Double click on combofix.exe & follow the prompts.
5. When finished, it will produce a report for you.
6. Please post the "C:\ComboFix.txt"

**Note 1: Do not mouseclick combofix's window while it's running. That may cause it to stall
**Note 2 for AVG users: ComboFix will not run until AVG is uninstalled as a protective measure against the anti-virus. This is because AVG "falsely" detects ComboFix (or its embedded files) as a threat and may remove them resulting in the tool not working correctly which in turn can cause "unpredictable results". Since AVG cannot be effectively disabled before running ComboFix, the author recommends you to uninstall AVG first.
Use AppRemover to uninstall it: Uninstall & Remove McAfee, Symantec, Norton, AVG, Avast & More Antivirus and Security Applications and Programs
We can reinstall it when we're done with CF.
**Note 3: If you receive an error "Illegal operation attempted on a registery key that has been marked for deletion", restart computer to fix the issue.



Make sure, you re-enable your security programs, when you're done with Combofix.

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ ~~~~~

NOTE.
If, for some reason, Combofix refuses to run, try one of the following:

1. Run Combofix from Safe Mode.

2. Delete Combofix file, download fresh one, but rename combofix.exe to your_name.exe BEFORE saving it to your desktop.
Do NOT run it yet.

Please download and run the below tool named Rkill (courtesy of BleepingComputer.com) which may help allow other programs to run.

There are 4 different versions. If one of them won't run then download and try to run the other one.

Vista and Win7 users need to right click Rkill and choose Run as Administrator

You only need to get one of these to run, not all of them. You may get warnings from your antivirus about this tool, ignore them or shutdown your antivirus.

Rkill.com
Rkill.scr
Rkill.exe

• Double-click on the Rkill desktop icon to run the tool.
• If using Vista or Windows 7 right-click on it and choose Run As Administrator.
• A black DOS box will briefly flash and then disappear. This is normal and indicates the tool ran successfully.
• If not, delete the file, then download and use the one provided in Link 2.
• If it does not work, repeat the process and attempt to use one of the remaining links until the tool runs.
• Do not reboot until instructed.
• If the tool does not run from any of the links provided, please let me know.

Once you've gotten one of them to run, immediately run your_name.exe by double clicking on it.

If normal mode still doesn't work, run BOTH tools from safe mode.

In case #2, please post BOTH logs, rKill and Combofix.

DO NOT make any other changes to your computer (like installing programs, using other cleaning tools, etc.), until it's officially declared clean!!!