can you please take a look at this for me thanks
Logfile of HijackThis v1.98.2
Scan saved at 12:30:34, on 18/10/2004
Platform: Windows XP (WinNT 5.01.2600)
MSIE: Internet Explorer v6.00 (6.00.2600.0000)

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\system32\spoolsv.exe
C:\WINDOWS\Explorer.EXE
C:\PROGRA~1\Grisoft\AVG6\avgserv.exe
C:\PROGRA~1\Grisoft\AVGTCP~1\avgtcpsv.exe
C:\WINDOWS\system32\cisvc.exe
C:\Program Files\Norton AntiVirus\navapsvc.exe
C:\WINDOWS\System32\RunDll32.exe
C:\WINDOWS\System32\sistray.EXE
C:\WINDOWS\System32\keyhook.exe
C:\Program Files\Gearbox Connection Kit\bin\confsvr.exe
C:\Program Files\TRUST\AMI MOUSE 150T OPTICAL WEB SCROLL\LWBWHEEL.exe
C:\WINDOWS\System32\rundll32.exe
C:\PROGRA~1\NORTON~1\navapw32.exe
C:\WINDOWS\System32\ctfmon.exe
C:\Program Files\Messenger\msmsgs.exe
C:\Program Files\Microsoft Money\System\reminder.exe
C:\Program Files\Sony Corporation\Picture Package\Picture Package Menu\SonyTray.exe
C:\Program Files\Sony Corporation\Picture Package\Picture Package Applications\Residence.exe
C:\Program Files\Gearbox Connection Kit\bin\gbConMon.exe
C:\Program Files\Gearbox Connection Kit\bin\gbTask.exe
C:\Program Files\Gearbox Connection Kit\bin\gbdash.exe
C:\Program Files\Outlook Express\msimn.exe
C:\WINDOWS\system32\cidaemon.exe
C:\Program Files\Internet Explorer\iexplore.exe
C:\Documents and Settings\D\Local Settings\Temp\Temporary Directory 2 for hijackthis.zip\HijackThis.exe

R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Page = http://red.clientapps.yahoo.com/cust.../www.yahoo.com
R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = http://www.ntlworld.com/home.html
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,SearchAssistant = http://www.123mania.com/0809/ie.asp
R1 - HKCU\Software\Microsoft\Internet Explorer\SearchURL,(Default) = http://red.clientapps.yahoo.com/cust.../www.yahoo.com
R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Int ernet Settings,ProxyOverride = ;<local>
R3 - URLSearchHook: SrchHook Class - {15651C7C-E812-44a2-A9AC-B467A2233E7D} - C:\WINDOWS\System32\GIDCAI32.dll
O2 - BHO: AcroIEHlprObj Class - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files\Adobe\Acrobat 5.0\Reader\ActiveX\AcroIEHelper.ocx
O2 - BHO: (no name) - {53707962-6F74-2D53-2644-206D7942484F} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O2 - BHO: BHOsrc Class - {622CC208-B014-4FE0-801B-874A5E5E403A} - C:\WINDOWS\System32\GIDCAI32.dll
O2 - BHO: HTML Class - {9C5B2F29-1F46-4639-A6B4-828942301D3E} - C:\WINDOWS\System32\SIPSPI32.dll
O2 - BHO: Core Library - {A23AB93D-6CFF-442c-BB8A-41F6145F47E7} - C:\WINDOWS\System32\PDF4ef3.dll
O2 - BHO: NAV Helper - {BDF3E430-B101-42AD-A544-FADC6B084872} - C:\Program Files\Norton AntiVirus\NavShExt.dll
O3 - Toolbar: &Radio - {8E718888-423F-11D2-876E-00A0C9082467} - C:\WINDOWS\System32\msdxm.ocx
O3 - Toolbar: Norton AntiVirus - {42CDD1BF-3FFB-4238-8AD1-7859DF00B1D6} - C:\Program Files\Norton AntiVirus\NavShExt.dll
O4 - HKLM\..\Run: [SiSUSBRG] C:\WINDOWS\SiSUSBrg.exe
O4 - HKLM\..\Run: [Cmaudio] RunDll32 cmicnfg.cpl,CMICtrlWnd
O4 - HKLM\..\Run: [SiS Tray] C:\WINDOWS\System32\sistray.EXE
O4 - HKLM\..\Run: [SiS Windows KeyHook] C:\WINDOWS\System32\keyhook.exe
O4 - HKLM\..\Run: [Gearbox] "C:\Program Files\Gearbox Connection Kit\bin\confsvr.exe"
O4 - HKLM\..\Run: [LWBMOUSE] C:\Program Files\TRUST\AMI MOUSE 150T OPTICAL WEB SCROLL\LWBWHEEL.exe
O4 - HKLM\..\Run: [PinnacleDriverCheck] C:\WINDOWS\System32\PSDrvCheck.exe -CheckReg
O4 - HKLM\..\Run: [LoadSIPS] rundll32.exe C:\WINDOWS\System32\SIPSPI32.dll,SIPSPI32
O4 - HKLM\..\Run: [SafeGuard Popup Updater (required)] regsvr32 /s C:\WINDOWS\System32\PDF4ef3.dll
O4 - HKLM\..\Run: [NAV Agent] C:\PROGRA~1\NORTON~1\navapw32.exe
O4 - HKLM\..\Run: [AVG_CC] C:\PROGRA~1\Grisoft\AVG6\avgcc32.exe /STARTUP
O4 - HKLM\..\RunServices: [Gearbox Deferal Check] C:\Program Files\Gearbox Connection Kit\bin\gbdefer.exe
O4 - HKCU\..\Run: [CTFMON.EXE] C:\WINDOWS\System32\ctfmon.exe
O4 - HKCU\..\Run: [MSMSGS] "C:\Program Files\Messenger\msmsgs.exe" /background
O4 - HKCU\..\Run: [Reminder] C:\Program Files\Microsoft Money\System\reminder.exe
O4 - Global Startup: Picture Package Menu.lnk = ?
O4 - Global Startup: Picture Package VCD Maker.lnk = ?
O9 - Extra button: Related - {c95fe080-8f5d-11d2-a20b-00aa003c157a} - C:\WINDOWS\web\related.htm
O9 - Extra 'Tools' menuitem: Show &Related Links - {c95fe080-8f5d-11d2-a20b-00aa003c157a} - C:\WINDOWS\web\related.htm
O12 - Plugin for .spop: C:\Program Files\Internet Explorer\Plugins\NPDocBox.dll
O16 - DPF: {78AF2F24-A9C3-11D3-BF8C-0060B0FCC122} (AcDcToday Control) - file://C:\Program Files\Autodesk Architectural Desktop 3\AcDcToday.ocx
O16 - DPF: {AE563720-B4F5-11D4-A415-00108302FDFD} (NOXLATE-BANR) - file://C:\Program Files\Autodesk Architectural Desktop 3\InstBanr.ocx
O16 - DPF: {C6637286-300D-11D4-AE0A-0010830243BD} (InstaFred) - file://C:\Program Files\Autodesk Architectural Desktop 3\InstFred.ocx
O16 - DPF: {F281A59C-7B65-11D3-8617-0010830243BD} (AcPreview Control) - file://C:\Program Files\Autodesk Architectural Desktop 3\AcPreview.ocx
O17 - HKLM\System\CCS\Services\Tcpip\..\{EF7CC936-3A37-494A-AE6F-913806577ED6}: NameServer = 194.168.4.100 194.168.8.100

Close all browser windows, restart Hijack This and put a checkmark next to the following entries:

R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Page = http://red.clientapps.yahoo.com/cus...//www.yahoo.com
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,SearchAssistant = http://www.123mania.com/0809/ie.asp
R1 - HKCU\Software\Microsoft\Internet Explorer\SearchURL,(Default) = http://red.clientapps.yahoo.com/cus...//www.yahoo.com
R3 - URLSearchHook: SrchHook Class - {15651C7C-E812-44a2-A9AC-B467A2233E7D} - C:\WINDOWS\System32\GIDCAI32.dll
O2 - BHO: BHOsrc Class - {622CC208-B014-4FE0-801B-874A5E5E403A} - C:\WINDOWS\System32\GIDCAI32.dll
O2 - BHO: HTML Class - {9C5B2F29-1F46-4639-A6B4-828942301D3E} - C:\WINDOWS\System32\SIPSPI32.dll
O2 - BHO: Core Library - {A23AB93D-6CFF-442c-BB8A-41F6145F47E7} - C:\WINDOWS\System32\PDF4ef3.dll
O4 - HKLM\..\Run: [LoadSIPS] rundll32.exe C:\WINDOWS\System32\SIPSPI32.dll,SIPSPI32
O4 - HKLM\..\Run: [SafeGuard Popup Updater (required)] regsvr32 /s C:\WINDOWS\System32\PDF4ef3.dll

Click Fix Checked

Reboot and post a fresh log

Thanks owen here is my new log
Logfile of HijackThis v1.98.2
Scan saved at 08:51:31, on 19/10/2004
Platform: Windows XP (WinNT 5.01.2600)
MSIE: Internet Explorer v6.00 (6.00.2600.0000)

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\Program Files\Sygate\SPF\smc.exe
C:\WINDOWS\Explorer.EXE
C:\WINDOWS\system32\spoolsv.exe
C:\PROGRA~1\Grisoft\AVG6\avgserv.exe
C:\WINDOWS\System32\RunDll32.exe
C:\WINDOWS\System32\sistray.EXE
C:\PROGRA~1\Grisoft\AVGTCP~1\avgtcpsv.exe
C:\WINDOWS\System32\keyhook.exe
C:\Program Files\Gearbox Connection Kit\bin\confsvr.exe
C:\Program Files\TRUST\AMI MOUSE 150T OPTICAL WEB SCROLL\LWBWHEEL.exe
C:\WINDOWS\system32\cisvc.exe
C:\PROGRA~1\Grisoft\AVG6\avgcc32.exe
C:\WINDOWS\System32\ctfmon.exe
C:\Program Files\Messenger\msmsgs.exe
C:\Program Files\Microsoft Money\System\reminder.exe
C:\Program Files\Gearbox Connection Kit\bin\gbConMon.exe
C:\Program Files\Gearbox Connection Kit\bin\gbTask.exe
C:\Documents and Settings\D\Local Settings\Temp\Temporary Directory 2 for hijackthis.zip\HijackThis.exe

R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = http://www.ntlworld.com/home.html
R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Int ernet Settings,ProxyOverride = ;<local>
O2 - BHO: AcroIEHlprObj Class - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files\Adobe\Acrobat 5.0\Reader\ActiveX\AcroIEHelper.ocx
O2 - BHO: (no name) - {53707962-6F74-2D53-2644-206D7942484F} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O3 - Toolbar: &Radio - {8E718888-423F-11D2-876E-00A0C9082467} - C:\WINDOWS\System32\msdxm.ocx
O4 - HKLM\..\Run: [SiSUSBRG] C:\WINDOWS\SiSUSBrg.exe
O4 - HKLM\..\Run: [Cmaudio] RunDll32 cmicnfg.cpl,CMICtrlWnd
O4 - HKLM\..\Run: [SiS Tray] C:\WINDOWS\System32\sistray.EXE
O4 - HKLM\..\Run: [SiS Windows KeyHook] C:\WINDOWS\System32\keyhook.exe
O4 - HKLM\..\Run: [Gearbox] "C:\Program Files\Gearbox Connection Kit\bin\confsvr.exe"
O4 - HKLM\..\Run: [LWBMOUSE] C:\Program Files\TRUST\AMI MOUSE 150T OPTICAL WEB SCROLL\LWBWHEEL.exe
O4 - HKLM\..\Run: [PinnacleDriverCheck] C:\WINDOWS\System32\PSDrvCheck.exe -CheckReg
O4 - HKLM\..\Run: [AVG_CC] C:\PROGRA~1\Grisoft\AVG6\avgcc32.exe /STARTUP
O4 - HKLM\..\Run: [SmcService] C:\PROGRA~1\Sygate\SPF\smc.exe -startgui
O4 - HKLM\..\RunServices: [Gearbox Deferal Check] C:\Program Files\Gearbox Connection Kit\bin\gbdefer.exe
O4 - HKCU\..\Run: [CTFMON.EXE] C:\WINDOWS\System32\ctfmon.exe
O4 - HKCU\..\Run: [MSMSGS] "C:\Program Files\Messenger\msmsgs.exe" /background
O4 - HKCU\..\Run: [Reminder] C:\Program Files\Microsoft Money\System\reminder.exe
O9 - Extra button: Related - {c95fe080-8f5d-11d2-a20b-00aa003c157a} - C:\WINDOWS\web\related.htm
O9 - Extra 'Tools' menuitem: Show &Related Links - {c95fe080-8f5d-11d2-a20b-00aa003c157a} - C:\WINDOWS\web\related.htm
O12 - Plugin for .spop: C:\Program Files\Internet Explorer\Plugins\NPDocBox.dll
O16 - DPF: {78AF2F24-A9C3-11D3-BF8C-0060B0FCC122} (AcDcToday Control) - file://C:\Program Files\Autodesk Architectural Desktop 3\AcDcToday.ocx
O16 - DPF: {AE563720-B4F5-11D4-A415-00108302FDFD} (NOXLATE-BANR) - file://C:\Program Files\Autodesk Architectural Desktop 3\InstBanr.ocx
O16 - DPF: {C6637286-300D-11D4-AE0A-0010830243BD} (InstaFred) - file://C:\Program Files\Autodesk Architectural Desktop 3\InstFred.ocx
O16 - DPF: {F281A59C-7B65-11D3-8617-0010830243BD} (AcPreview Control) - file://C:\Program Files\Autodesk Architectural Desktop 3\AcPreview.ocx

Thats a clean log, how are things running?

Thanks I have had no more problems you have been a great help

Preventing it returning

After your problem has been resolved on the forum, it is an absoulute MUST to do the following steps to prevent the problem returning. Click on the link to get access to the software or webpage that I'm referring to.

1. Visit Windows Update
Pay a visit to Windows Update and scan for and download ALL Critical Updates and Service Packs. New updates are usually released monthly so check back to Windows Update every month.

2. Download Antivirus Software-
If you haven't already got Antivirus software, you should download and install AVG Antivirus. It is freeware and is updated nearly every 2 days (sometimes more frequently if there are a lot of new viruses) and in my opinion, is better than some Antivirus software such as Norton. Antivirus software will prevent viruses infecting your system and it is important that you update it every two days or every week at the most.

3. Download a Firewall-
If you haven't already got a firewall, it is Very important that you download one. Firewalls will prevent unauthorised access to your computer and stop data leaking out of your computer. You may think that it won't happen to you, but Hackers don't care who you are, what you do, where you live or what you had for tea last Sunday on your holiday in the Lake District, they want your data. Firewalls will keep these sneaks out and one of the best is Sygate Personal Firewall, which happens to be freeware.

4. Spyware Scanners-
It is important that as well as having real time spyware protection, you have a spyware scanning application. If you have not already been told to download one earlier in this thread, it is a good idea to download Spybot Search And Destroy and Ad-aware. They are both spyware scanners and will search for a remove spyware. It is recommended that you have both, because one will pick up entries that the other misses. It is even a good idea to download these if you have other programs such as ASE, Spysweeper, Pest Patrol, etc, because one spyware scanner will not pick up everything. Please remember to update your spyware scanners weekly/fortnightly.

5. Prevent Spyware slipping through Internet Explorer-
Quite a lot of spyware slips through Internet Explorer if your settings are not tight enough. Spyware Blaster will help you prevent spyware slipping through and installing tracking cookies. Simply run it via Start> Programs> Spyware Blaster and click Enable All Protection and it will protect you. It doesn't even have to be open! Remember to update weekly/fortnightly.

6. Constant Spyware Protection-
It is important to have constant spyware protection. Spyware Guard works like an antivirus program but detects Spyware instead. It will constantly protect your system. Check for updates monthly.

All Of these steps are very important and it is HIGHLY recommended that you download all of the programs mentioned for your own safety. Remember to Update everything (including Windows using Windows Update)! It is also a good idea to perform weekly/fortnightly scans with Spybot S&D, Ad-aware and your antivirus software.

And last of all, please remember, that common sense is your greatest tool. Without it, spyware and other related Malware would rule!