Below is a HiJack This log from a computer that was infected with XP AntiSpyware 2009. I've run Malewarebytes, Spybot and AdAware in addition to Avast Virus Scan, in Windows and Safe Mode yet I still get the browser hi jacked and cannot get rid of the following entries:
O4 HKLM|...|Run:[tedutigugu....
O4 HKLM\...\Run:[e05f8b47....
O4 HKLM\...\Run:[CPMe36cb8db...
O4 HKLS\S-1-5-19\..\Run:[tedutigug....
O4 HKLS\S-1-5-20\..\Run:[tedutigug....
O20-AppInit_DLLs: C:\Windows...Meyopoli.dll c:\windows...refobaju.dll
O21-SSODL _ {EC43E3FD-...} c:\windows...\refobaju.dll
O22-SharedTaskScheduler:STS -{EC43E3FD...}c:\windows...refobaju.dll

I've removed them in Safe Mode manually with regedit and HiJack this but on reboot they come back the next time I scan and save a log.

Additionally automatic updates keeps turning off and I can't access Windows Update. I get a blank page with Done in the status bar. I've been able to manually browse to Microsoft Update and download updates from there but none of the updates has cleared up this problem.

The computer keeps trying to load the jumidani.dll file on startup and throws an error message that the file is missing. Additionally I get a popup of the C:\Program Files\Common folder at Windows start up too.

Research on refobaju.dll, jumidani.dll has turned up nothing. I suspect this is something new.

Here is the entire HiJack This log:

Logfile of Trend Micro HijackThis v2.0.2
Scan saved at 9:19:16 AM, on 12/10/2008
Platform: Windows XP SP3 (WinNT 5.01.2600)
MSIE: Internet Explorer v7.00 (7.00.6000.16762)
Boot mode: Normal

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\Program Files\Lavasoft\Ad-Aware\aawservice.exe
C:\Program Files\Alwil Software\Avast4\aswUpdSv.exe
C:\Program Files\Alwil Software\Avast4\ashServ.exe
C:\WINDOWS\system32\spoolsv.exe
C:\WINDOWS\Explorer.EXE
C:\Program Files\Java\jre6\bin\jqs.exe
C:\Program Files\Analog Devices\Core\smax4pnp.exe
C:\Program Files\Java\jre6\bin\jusched.exe
C:\Program Files\HP\HP Software Update\HPWuSchd2.exe
C:\Program Files\iTunes\iTunesHelper.exe
C:\PROGRA~1\ALWILS~1\Avast4\ashDisp.exe
C:\WINDOWS\system32\rundll32.exe
C:\WINDOWS\system32\ctfmon.exe
C:\Documents and Settings\All Users\Application Data\Dell\TransferAgent\TransferAgent.exe
C:\Program Files\Microsoft SQL Server\MSSQL$ALAMODE\Binn\sqlservr.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\system32\SearchIndexer.exe
C:\Program Files\Alwil Software\Avast4\ashMaiSv.exe
C:\Program Files\Alwil Software\Avast4\ashWebSv.exe
C:\Program Files\iPod\bin\iPodService.exe
C:\Program Files\Google\GoogleToolbarNotifier\GoogleToolbarNo tifier.exe
C:\Program Files\HP\Digital Imaging\bin\hpqtra08.exe
C:\Program Files\Kodak\Kodak EasyShare software\bin\EasyShare.exe
C:\Program Files\Kodak\KODAK Software Updater\7288971\Program\Kodak Software Updater.exe
C:\Program Files\HP\Digital Imaging\bin\hpqgalry.exe
C:\Program Files\Windows Desktop Search\WindowsSearch.exe
C:\Program Files\Trend Micro\HijackThis\HijackThis.exe

R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Page = http://go.microsoft.com/fwlink/?LinkId=54896
R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page =
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://go.microsoft.com/fwlink/?LinkId=69157
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = http://go.microsoft.com/fwlink/?LinkId=54896
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = http://go.microsoft.com/fwlink/?LinkId=54896
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = http://go.microsoft.com/fwlink/?LinkId=69157
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,SearchAssistant =
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,CustomizeSearch =
O2 - BHO: Adobe PDF Reader Link Helper - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files\Common Files\Adobe\Acrobat\ActiveX\AcroIEHelper.dll
O2 - BHO: Spybot-S&D IE Protection - {53707962-6F74-2D53-2644-206D7942484F} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O2 - BHO: Java(tm) Plug-In SSV Helper - {761497BB-D6F0-462C-B6EB-D4DAF1D92D43} - C:\Program Files\Java\jre6\bin\ssv.dll
O2 - BHO: (no name) - {94991a32-d692-4797-8f2d-bd7322bfa729} - C:\WINDOWS\system32\refodegu.dll (file missing)
O2 - BHO: Google Toolbar Helper - {AA58ED58-01DD-4d91-8333-CF10577473F7} - c:\program files\google\googletoolbar1.dll
O2 - BHO: Google Toolbar Notifier BHO - {AF69DE43-7D58-4638-B6FA-CE66B5AD205D} - C:\Program Files\Google\GoogleToolbarNotifier\2.1.615.5858\sw g.dll
O2 - BHO: Java(tm) Plug-In 2 SSV Helper - {DBC80044-A445-435b-BC74-9C25C1C588A9} - C:\Program Files\Java\jre6\bin\jp2ssv.dll
O2 - BHO: JQSIEStartDetectorImpl - {E7E6F031-17CE-4C07-BC86-EABFE594F69C} - C:\Program Files\Java\jre6\lib\deploy\jqs\ie\jqs_plugin.dll
O3 - Toolbar: &Google - {2318C2B1-4965-11d4-9B18-009027A5CD4F} - c:\program files\google\googletoolbar1.dll
O4 - HKLM\..\Run: [SoundMAXPnP] C:\Program Files\Analog Devices\Core\smax4pnp.exe
O4 - HKLM\..\Run: [SunJavaUpdateSched] "C:\Program Files\Java\jre6\bin\jusched.exe"
O4 - HKLM\..\Run: [HP Software Update] C:\Program Files\HP\HP Software Update\HPWuSchd2.exe
O4 - HKLM\..\Run: [iTunesHelper] "C:\Program Files\iTunes\iTunesHelper.exe"
O4 - HKLM\..\Run: [avast!] C:\PROGRA~1\ALWILS~1\Avast4\ashDisp.exe
O4 - HKLM\..\Run: [tedutigugu] Rundll32.exe "C:\WINDOWS\system32\jumidani.dll",s
O4 - HKLM\..\Run: [e05f8b47] rundll32.exe "C:\WINDOWS\system32\rivunepi.dll",b
O4 - HKLM\..\Run: [CPMe36cb8db] Rundll32.exe "c:\windows\system32\refobaju.dll",a
O4 - HKCU\..\Run: [ctfmon.exe] C:\WINDOWS\system32\ctfmon.exe
O4 - HKCU\..\Run: [DellTransferAgent] "C:\Documents and Settings\All Users\Application Data\Dell\TransferAgent\TransferAgent.exe"
O4 - HKCU\..\Run: [AdobeUpdater] C:\Program Files\Common Files\Adobe\Updater5\AdobeUpdater.exe
O4 - HKCU\..\Run: [swg] C:\Program Files\Google\GoogleToolbarNotifier\GoogleToolbarNo tifier.exe
O4 - HKUS\S-1-5-19\..\Run: [tedutigugu] Rundll32.exe "C:\WINDOWS\system32\jumidani.dll",s (User 'LOCAL SERVICE')
O4 - HKUS\S-1-5-20\..\Run: [tedutigugu] Rundll32.exe "C:\WINDOWS\system32\jumidani.dll",s (User 'NETWORK SERVICE')
O4 - Global Startup: Adobe Gamma Loader.lnk = C:\Program Files\Common Files\Adobe\Calibration\Adobe Gamma Loader.exe
O4 - Global Startup: HP Digital Imaging Monitor.lnk = C:\Program Files\HP\Digital Imaging\bin\hpqtra08.exe
O4 - Global Startup: HP Image Zone Fast Start.lnk = C:\Program Files\HP\Digital Imaging\bin\hpqthb08.exe
O4 - Global Startup: Kodak EasyShare software.lnk = C:\Program Files\Kodak\Kodak EasyShare software\bin\EasyShare.exe
O4 - Global Startup: Kodak software updater.lnk = C:\Program Files\Kodak\KODAK Software Updater\7288971\Program\Kodak Software Updater.exe
O4 - Global Startup: Microsoft Office.lnk = C:\Program Files\Microsoft Office\Office\OSA9.EXE
O4 - Global Startup: QuickBooks Update Agent.lnk = C:\Program Files\Common Files\Intuit\QuickBooks\QBUpdate\qbupdate.exe
O4 - Global Startup: Windows Search.lnk = C:\Program Files\Windows Desktop Search\WindowsSearch.exe
O9 - Extra button: Send to OneNote - {2670000A-7350-4f3c-8081-5663EE0C6C49} - C:\PROGRA~1\MICROS~4\Office12\ONBttnIE.dll
O9 - Extra 'Tools' menuitem: S&end to OneNote - {2670000A-7350-4f3c-8081-5663EE0C6C49} - C:\PROGRA~1\MICROS~4\Office12\ONBttnIE.dll
O9 - Extra button: AIM - {AC9E2541-2814-11d5-BC6D-00B0D0A1DE45} - C:\Program Files\AIM\aim.exe
O9 - Extra button: Real.com - {CD67F990-D8E9-11d2-98FE-00C0F0318AFE} - C:\WINDOWS\system32\Shdocvw.dll
O9 - Extra button: (no name) - {DFB852A3-47F8-48C4-A200-58CAB36FD2A2} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O9 - Extra 'Tools' menuitem: Spybot - Search & Destroy Configuration - {DFB852A3-47F8-48C4-A200-58CAB36FD2A2} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O9 - Extra 'Tools' menuitem: Windows Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O16 - DPF: {01113300-3E00-11D2-8470-0060089874ED} (Support.com Configuration Class) - http://activation.rr.com/install/download/tgctlcm.cab
O16 - DPF: {48DD0448-9209-4F81-9F6D-D83562940134} (MySpace Uploader Control) - http://lads.myspace.com/upload/MySpaceUploader1006.cab
O16 - DPF: {4989312D-58CF-11D5-A7D7-00E02911103E} (Interealty MultiSelect) - http://sar.mlxchange.com/Control/Mul...ctComboBox.cab
O16 - DPF: {4F1E5B1A-2A80-42CA-8532-2D05CB959537} (MSN Photo Upload Tool) - http://gfx1.hotmail.com/mail/w2/pr02...s/MSNPUpld.cab
O16 - DPF: {5D86DDB5-BDF9-441B-9E9E-D4730F4EE499} (BDSCANONLINE Control) - http://download.bitdefender.com/reso...an8/oscan8.cab
O16 - DPF: {62789780-B744-11D0-986B-00609731A21D} (Autodesk MapGuide ActiveX Control) - http://mapguide.stpete.org/mgaxctrl.cab
O16 - DPF: {6FD482A3-7B57-438B-B040-52CAA30147EE} (MLXchange Client Utils) - http://sar.mlxchange.com/Control/MLXClientUtils.cab
O16 - DPF: {83AB6E4D-CDD7-11D3-B5E7-00104B9AFF6E} (GeacRevw Control) - http://sar.mlxchange.com/Control/IRCSharc.cab
O16 - DPF: {D27CDB6E-AE6D-11CF-96B8-444553540000} (Shockwave Flash Object) - http://fpdownload2.macromedia.com/ge...nt/swflash.cab
O18 - Filter hijack: text/html - {b7f16a6b-54fa-4cd5-8126-913a759d1303} - C:\WINDOWS\system32\msiebbar.dll
O20 - AppInit_DLLs: C:\WINDOWS\system32\meyopoli.dll c:\windows\system32\refobaju.dll
O21 - SSODL: SSODL - {EC43E3FD-5C60-46a6-97D7-E0B85DBDD6C4} - c:\windows\system32\refobaju.dll
O22 - SharedTaskScheduler: STS - {EC43E3FD-5C60-46a6-97D7-E0B85DBDD6C4} - c:\windows\system32\refobaju.dll
O23 - Service: Lavasoft Ad-Aware Service (aawservice) - Lavasoft - C:\Program Files\Lavasoft\Ad-Aware\aawservice.exe
O23 - Service: avast! iAVS4 Control Service (aswUpdSv) - ALWIL Software - C:\Program Files\Alwil Software\Avast4\aswUpdSv.exe
O23 - Service: avast! Antivirus - ALWIL Software - C:\Program Files\Alwil Software\Avast4\ashServ.exe
O23 - Service: avast! Mail Scanner - ALWIL Software - C:\Program Files\Alwil Software\Avast4\ashMaiSv.exe
O23 - Service: avast! Web Scanner - ALWIL Software - C:\Program Files\Alwil Software\Avast4\ashWebSv.exe
O23 - Service: DSBrokerService - Unknown owner - C:\Program Files\DellSupport\brkrsvc.exe
O23 - Service: Google Updater Service (gusvc) - Google - C:\Program Files\Google\Common\Google Updater\GoogleUpdaterService.exe
O23 - Service: InstallDriver Table Manager (IDriverT) - Macrovision Corporation - C:\Program Files\Common Files\InstallShield\Driver\1050\Intel 32\IDriverT.exe
O23 - Service: iPod Service - Apple Inc. - C:\Program Files\iPod\bin\iPodService.exe
O23 - Service: Java Quick Starter (JavaQuickStarterService) - Sun Microsystems, Inc. - C:\Program Files\Java\jre6\bin\jqs.exe
O23 - Service: Intel NCS NetService (NetSvc) - Intel(R) Corporation - C:\Program Files\Intel\PROSetWired\NCS\Sync\NetSvc.exe
O23 - Service: Pml Driver HPZ12 - HP - C:\WINDOWS\system32\HPZipm12.exe
O23 - Service: PC Tools Auxiliary Service (sdAuxService) - PC Tools - C:\Program Files\Spyware Doctor\svcntaux.exe
O23 - Service: PC Tools Security Service (sdCoreService) - PC Tools - C:\Program Files\Spyware Doctor\swdsvc.exe

--
End of file - 10074 bytes

Help with this would be highly appreciated.

Thanks in advance.

The problem with the malware recurring is due to the 020_AppInit_DDLs:c:\Windows... meyopoli.dll c:\Windows... refobaju.dll entry.
AppInit_DDLs is a little used windows feature that loads .dll files very early in the boot process. Even if you've tried to unclick the entries in msconfig you'll find they are coming back too. First you'll need an anti-spyware program. If you don't have one I recommend Spybot-Seach and Destroy. http:\\www.spybot.com. Once it's downloaded open it and click "search for updates". Find an appropriate server and update Spybot.

You seem pretty tech savvy but I'm going to describe the process to remove you're malware at length in case some else might run into this post.

1. Once Spybot is loaded and updated reboot into safe mode.

2. Open msconfig ( goto- start- run- type msconfig and then enter) Once msconfig opens click the startup tab and unclick any unwanted entries. click "apply" then "close" and you will be prompted to reboot but choose the "exit without restart" option.

3. Open HijackThis. Click the "Delete a file on reboot" tab. This will delete the file before it has a chance to open itself.

4. Once it opens navigate to c:\Windows\System32. Select one of the files listed in your HijackThis log. Click the "open" tab and then choose "do not restart". You will have to repeat this process until all of the offending .dll files have been deleted.

5. Reboot into safe mode and run HijackThis again. Do a system scan and remove any other registry entries that may still be there.

6. Run Spybot and scan your system for malware. Once the scan is complete click "fix selected problems".

7. Reboot normally and you should be back in business!

I cured the problem but it took more than Spybot to fix it.

Was AppInit_DLLs the problem?