I have run Hijack and this is the result:

unning processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\Program Files\Common Files\Symantec Shared\ccSetMgr.exe
C:\Program Files\Common Files\Symantec Shared\ccEvtMgr.exe
C:\WINDOWS\Explorer.EXE
C:\WINDOWS\system32\spoolsv.exe
C:\Program Files\Norton AntiVirus\navapsvc.exe
C:\WINDOWS\System32\qttask.exe
C:\WINDOWS\System32\nvsvc32.exe
C:\Program Files\Norton AntiVirus\SAVScan.exe
C:\WINDOWS\System32\svchost.exe
C:\Program Files\Common Files\Symantec Shared\ccApp.exe
C:\WINDOWS\System32\spool\DRIVERS\W32X86\3\E_S10IC 2.EXE
C:\Program Files\Common Files\Symantec Shared\CCPD-LC\symlcsvc.exe
C:\Program Files\Messenger\msmsgs.exe
C:\Program Files\Sony Corporation\Image Transfer\SonyTray.exe
C:\Program Files\Sony\VAIO Action Setup\VAServ.exe
C:\WINDOWS\system32\winlogon.exe
C:\Program Files\Internet Explorer\iexplore.exe
C:\Documents and Settings\Geoff\Local Settings\Temporary Internet Files\Content.IE5\ET5QJEPO\HijackThis[1].exe

R1 - HKCU\Software\Microsoft\Internet Explorer,SearchURL = c:\searchpage.html#1507
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Bar = c:\searchpage.html#1507
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Page = c:\searchpage.html#1507
R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = c:\searchpage.html#1507
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = c:\searchpage.html#1507
R1 - HKCU\Software\Microsoft\Internet Explorer\Search,SearchAssistant = c:\searchpage.html#1507
R1 - HKCU\Software\Microsoft\Internet Explorer\Search,CustomizeSearch = c:\searchpage.html#1507
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = c:\searchpage.html#1507
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = c:\searchpage.html#1507
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = c:\searchpage.html#1507
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,CustomizeSearch = c:\searchpage.html#1507
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,SearchAssistant = c:\searchpage.html#1507
R1 - HKCU\Software\Microsoft\Internet Explorer,Search = c:\searchpage.html#1507
R1 - HKLM\Software\Microsoft\Internet Explorer,Search = c:\searchpage.html#1507
O2 - BHO: (no name) - {98DBBF16-CA43-4c33-BE80-99E6694468A4} - C:\WINDOWS\System32\msmk.dll
O3 - Toolbar: &Radio - {8E718888-423F-11D2-876E-00A0C9082467} - C:\WINDOWS\System32\msdxm.ocx
O3 - Toolbar: Norton AntiVirus - {42CDD1BF-3FFB-4238-8AD1-7859DF00B1D6} - C:\Program Files\Norton AntiVirus\NavShExt.dll
O4 - HKLM\..\Run: [NvCplDaemon] RUNDLL32.EXE C:\WINDOWS\System32\NvCpl.dll,NvStartup
O4 - HKLM\..\Run: [QuickTime Task] C:\WINDOWS\System32\qttask.exe
O4 - HKLM\..\Run: [nwiz] nwiz.exe /install
O4 - HKLM\..\Run: [HP OfficeJet Series 600] "C:\Program Files\Hewlett-Packard\HP OfficeJet Series 600\bin\ktchnsnk.exe" -reg "Software\Hewlett-Packard\OfficeJet Series 600\Install"
O4 - HKLM\..\Run: [ccApp] "C:\Program Files\Common Files\Symantec Shared\ccApp.exe"
O4 - HKLM\..\Run: [EPSON Stylus CX6400] C:\WINDOWS\System32\spool\DRIVERS\W32X86\3\E_S10IC 2.EXE /P19 "EPSON Stylus CX6400" /O6 "USB001" /M "Stylus CX6400"
O4 - HKCU\..\Run: [MSMSGS] "C:\Program Files\Messenger\msmsgs.exe" /background
O4 - Global Startup: Adobe Gamma Loader.exe.lnk = C:\Program Files\Common Files\Adobe\Calibration\Adobe Gamma Loader.exe
O4 - Global Startup: Image Transfer.lnk = ?
O4 - Global Startup: Microsoft Office.lnk = C:\Program Files\Microsoft Office\Office10\OSA.EXE
O4 - Global Startup: VAIO Action Setup (Server).lnk = ?
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~1\MICROS~2\Office10\EXCEL.EXE/3000
O9 - Extra button: Real.com (HKLM)
O9 - Extra button: Messenger (HKLM)
O9 - Extra 'Tools' menuitem: Windows Messenger (HKLM)
O12 - Plugin for .spop: C:\Program Files\Internet Explorer\Plugins\NPDocBox.dll
O13 - DefaultPrefix: c:\searchpage.html?page=
O13 - WWW Prefix: c:\searchpage.html?page=
O13 - Home Prefix: c:\searchpage.html?page=
O13 - Mosaic Prefix: c:\searchpage.html?page=
O14 - IERESET.INF: START_PAGE_URL=http://www.club-vaio.sony-europe.com
O15 - Trusted Zone: *.Sony-europe.com
O15 - Trusted Zone: *.Sonystyle-europe.com
O16 - DPF: {166B1BCA-3F9C-11CF-8075-444553540000} (Shockwave ActiveX Control) - http://download.macromedia.com/pub/s...irector/sw.cab
O16 - DPF: {3E68E405-C6DE-49FF-83AE-41EE9F4C36CE} (Office Update Installation Engine) - http://office.microsoft.com/officeup...ntent/opuc.cab
O16 - DPF: {4E888414-DB8F-11D1-9CD9-00C04F98436A} (Microsoft.WinRep) - https://webresponse.one.microsoft.co...veX/winrep.cab
O16 - DPF: {556DDE35-E955-11D0-A707-000000521957} - http://www.xblock.com/download/xclean_micro.exe
O16 - DPF: {C56CE781-A6FC-4706-8B32-6EB4622155DF} (MediaConnect Control) - http://plugin.euro-infomedia.com/mpv0.cab
O16 - DPF: {CE3409C4-9E26-4F8E-83E4-778498F9E7B4} (PB_Uploader Class) - http://static.photobox.co.uk/sg/common/uploader.ocx
O16 - DPF: {D27CDB6E-AE6D-11CF-96B8-444553540000} (Shockwave Flash Object) - http://download.macromedia.com/pub/s...sh/swflash.cab
O16 - DPF: {E855A2D4-987E-4F3B-A51C-64D10A7E2479} (EPSImageControl Class) - http://tools.ebayimg.com/eps/activex...l_v1-0-3-0.cab

Can I remove all the entries ending in :searchpage.html#1507

Please help

Hi Geoff, first download, update and run
CWShredder
Click Fix, don't just scan. Let it fix everything it asks about.

Restart HijackThis and put checks next to the following (if they are still present), close all browser windows (including this one) then click on 'Fix Checked':


R1 - HKCU\Software\Microsoft\Internet Explorer,SearchURL = c:\searchpage.html#1507
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Bar = c:\searchpage.html#1507
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Page = c:\searchpage.html#1507
R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = c:\searchpage.html#1507
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = c:\searchpage.html#1507
R1 - HKCU\Software\Microsoft\Internet Explorer\Search,SearchAssistant = c:\searchpage.html#1507
R1 - HKCU\Software\Microsoft\Internet Explorer\Search,CustomizeSearch = c:\searchpage.html#1507
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = c:\searchpage.html#1507
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = c:\searchpage.html#1507
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = c:\searchpage.html#1507
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,CustomizeSearch = c:\searchpage.html#1507
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,SearchAssistant = c:\searchpage.html#1507
R1 - HKCU\Software\Microsoft\Internet Explorer,Search = c:\searchpage.html#1507
R1 - HKLM\Software\Microsoft\Internet Explorer,Search = c:\searchpage.html#1507
O2 - BHO: (no name) - {98DBBF16-CA43-4c33-BE80-99E6694468A4} - C:\WINDOWS\System32\msmk.dll


O13 - DefaultPrefix: c:\searchpage.html?page=
O13 - WWW Prefix: c:\searchpage.html?page=
O13 - Home Prefix: c:\searchpage.html?page=
O13 - Mosaic Prefix: c:\searchpage.html?page=

Reboot, then post a fresh log.

Hi Nirvana

Thanks a mill for the help. It looks much better now and my home page address is no longer lost.
R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = http://www.piperanddrummer.com/
O3 - Toolbar: &Radio - {8E718888-423F-11D2-876E-00A0C9082467} - C:\WINDOWS\System32\msdxm.ocx
O3 - Toolbar: Norton AntiVirus - {42CDD1BF-3FFB-4238-8AD1-7859DF00B1D6} - C:\Program Files\Norton AntiVirus\NavShExt.dll
O4 - HKLM\..\Run: [NvCplDaemon] RUNDLL32.EXE C:\WINDOWS\System32\NvCpl.dll,NvStartup
O4 - HKLM\..\Run: [QuickTime Task] C:\WINDOWS\System32\qttask.exe
O4 - HKLM\..\Run: [nwiz] nwiz.exe /install
O4 - HKLM\..\Run: [ccApp] "C:\Program Files\Common Files\Symantec Shared\ccApp.exe"
O4 - HKLM\..\Run: [EPSON Stylus CX6400] C:\WINDOWS\System32\spool\DRIVERS\W32X86\3\E_S10IC 2.EXE /P19 "EPSON Stylus CX6400" /O6 "USB001" /M "Stylus CX6400"
O4 - HKCU\..\Run: [MSMSGS] "C:\Program Files\Messenger\msmsgs.exe" /background
O4 - Global Startup: Adobe Gamma Loader.exe.lnk = C:\Program Files\Common Files\Adobe\Calibration\Adobe Gamma Loader.exe
O4 - Global Startup: Image Transfer.lnk = ?
O4 - Global Startup: Microsoft Office.lnk = C:\Program Files\Microsoft Office\Office10\OSA.EXE
O4 - Global Startup: VAIO Action Setup (Server).lnk = ?
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~1\MICROS~2\Office10\EXCEL.EXE/3000
O9 - Extra button: Real.com (HKLM)
O9 - Extra button: Messenger (HKLM)
O9 - Extra 'Tools' menuitem: Windows Messenger (HKLM)
O12 - Plugin for .spop: C:\Program Files\Internet Explorer\Plugins\NPDocBox.dll
O14 - IERESET.INF: START_PAGE_URL=http://www.club-vaio.sony-europe.com
O15 - Trusted Zone: *.Sony-europe.com
O15 - Trusted Zone: *.Sonystyle-europe.com
O16 - DPF: {02C20140-76F8-4763-83D5-B660107B7A90} (Moniker32 Class) - http://63.219.181.7/cax.cab
O16 - DPF: {166B1BCA-3F9C-11CF-8075-444553540000} (Shockwave ActiveX Control) - http://download.macromedia.com/pub/s...irector/sw.cab
O16 - DPF: {3E68E405-C6DE-49FF-83AE-41EE9F4C36CE} (Office Update Installation Engine) - http://office.microsoft.com/officeup...ntent/opuc.cab
O16 - DPF: {4E888414-DB8F-11D1-9CD9-00C04F98436A} (Microsoft.WinRep) - https://webresponse.one.microsoft.co...veX/winrep.cab
O16 - DPF: {556DDE35-E955-11D0-A707-000000521957} - http://www.xblock.com/download/xclean_micro.exe
O16 - DPF: {C56CE781-A6FC-4706-8B32-6EB4622155DF} (MediaConnect Control) - http://plugin.euro-infomedia.com/mpv0.cab
O16 - DPF: {CE3409C4-9E26-4F8E-83E4-778498F9E7B4} (PB_Uploader Class) - http://static.photobox.co.uk/sg/common/uploader.ocx
O16 - DPF: {D27CDB6E-AE6D-11CF-96B8-444553540000} (Shockwave Flash Object) - http://download.macromedia.com/pub/s...sh/swflash.cab
O16 - DPF: {E855A2D4-987E-4F3B-A51C-64D10A7E2479} (EPSImageControl Class) - http://tools.ebayimg.com/eps/activex...l_v1-0-3-0.cab

Many thanks

Cheers
Geoff